URINE DRUG SCREENING METHODOLOGY

All urine specimens are screened using enzyme immunoassay (EIA) on state of the art equipment.

	SCREENING CUT-OFF LEVELS BY EIA
	Drugs of Abuse		EIA Cut-off
	Amphetamine		1000 ng/mL
	Methamphetamine		1000 ng/mL
	Barbiturates		200 ng/mL
	Benzodiazepines		200 ng/mL
	Buprenorphine		5 ng/mL
	Cocaine Metabolite (Benzoylecgonine)		300 ng/mL
	Ethanol		0.04gm/dL
	Methadone		150 ng/mL
	Methadone Metabolite		150 ng/mL
	Methaqualone		300 ng/mL
	Opiates (morphine and codeine)		300 ng/mL
	Oxycodone		300 ng/mL
	Phencyclidine		25 ng/mL
	Propoxyphene		300 ng/mL
	THC (cannabinoids)		20/50 ng/mL*

*Agency has the ability to choose cut-off levels indicated.

URINE DRUG TEST CONFIRMATION METHODOLOGY

Specimens are confirmed with radioimmunoassay (RIA), thin layer chromatography (TLC), gas chromatography (GC), and/or gas chromatography/mass spectrometry (GC/MS).

	CONFIRMATION CUT-OFF LEVELS BY PROCEDURE
	Drug		TLC		RIA		GC/MS
	Amphetamines  - Amphetamine  - Methamphetamine  - MDMA  - MDA		< 500 ng/mL < 500 ng/mL < 500 ng/mL < 500 ng/mL				100 ng/mL 100 ng/mL 100 ng/mL 100 ng/mL
	Barbiturates		< 500 ng/mL				200 ng/mL
	Benzodiazepines				200 ng/mL		50 ng/mL
	Buprenorphine						0.5 ng/mL
	Cocaine metabolite (Benzoylecgonine)				150 ng/mL		50 ng/mL
	EtG (LC/MS/MS)**						100 ng/mL
	EtS (LC/MS/MS)**						25 ng/mL
	Fentanyl						5 ng/mL
	GHB						10 mcg/mL
	6-Monoacetylmorphine						5 ng/mL
	Marijuana Metabolite (THC-COOH)				25 ng/mL		5 ng/mL
	Methadone		< 500 ng/mL				100 ng/mL
	Methaqualone		< 500 ng/mL
	Opiates     - Total Morphine     - Codeine     - Hydrocodone     - Hydromorphone     - Oxycodone		< 500 ng/mL < 500 ng/mL 1000 ng/mL   1000 ng/mL				100 ng/mL 100 ng/mL 100 ng/mL 100 ng/mL 100 ng/mL
	Phencyclidine (PCP)						10 ng/mL
	Propoxyphene		< 500 ng/mL				200 ng/mL
	Ethanol (GC-FID)***						.02 gm/dL

** Test performed by Liquid Chromatography / Mass Spectrometry / Mass Spectrometry
*** Test performed by Gas Chromatography Flame Ionization Detection.

URINALYSIS ADULTERATION EXAMINATION

RTL’s Standard Operating Procedures (SOP's) require that each urine specimen be examined for signs of adulteration. This examination includes the following:

Physical Examination: Color, excessive foaming, excess sediments, or unusual odor are noted. If adulteration is suspected, this is noted on the final report.

Analytical Examination: Upon request, pH, creatinine (tested by default) and specific gravity are run to aid in determining possible adulteration.

RTL also offers on-site test devices. Click here to view the complete line of Reditest^® screening devices.

Drug information data is not definitive and should be used for reference guidelines only.

The Resource Library includes information available in our printed Reference Guide, delivered to all new clients. If you would like to have a copy sent to you, please contact a sales representative at 800-255-2159.